News
Find a list of 454 Life Sciences™'s press releases below:
- 2/28/2013
Roche and Hamilton Introduce New Automated DNA Sample Enrichment Platform for GS Junior Sequencing Instruments
Today Roche and Hamilton Robotics jointly announced the introduction of a new, integrated platform enabling automated DNA sample enrichment for Roche’s 454 GS Junior sequencer. - 2/28/2013
First European laboratory obtains accreditation for new tissue typing method for stem cell transplants
Tests based on next-generation sequencing with Roche’s GS Junior System - 2/23/2013
Research consortium announces significant progress to close gaps and uncover novel genes in the Human Reference Genome Sequence
High quality long-read sequencing technology is providing new insights into previously unsequenced regions of the Human Reference Genome - 12/21/2012
Roche and PSS sign agreement to develop a fully automated workflow solution for next-generation sequencing platforms - 12/12/2012
Roche 454 Sequencing Systems successfully resolve genetic mutations in over 4,000 blood cancer cases
International study presented at American Society of Hematology Meeting demonstrates the potential of 454 Sequencing Systems to comprehensively characterize an individual’s blood cancer type to guide personalized therapy decisions. - 11/7/2012
Roche introduces new GS FLX+ software for significantly improved long-read sequencing performance
First high-throughput sequencing platform to deliver one million reads with read lengths of up to 1000 bp and beyond - 5/15/2012
BGI Installs Roche GS FLX+ System to Enhance Long Read Sequencing Capabilities for Genome and Transcriptome Research
BGI's new GS FLX+ System will complement its existing array of short read sequencing technologies and enhance BGI’s long read sequencing capability. - 5/9/2012
Roche 454 Life Sciences and SoftGenetics Sign Co-Promotion Agreement for Next-Gen Sequencing Software Tools
The two companies will co-promote Roche 454 Sequencing Systems and SoftGenetics NextGENe® software. - 4/24/2012
Roche Launches 454 Sequencing Assays for High Sensitivity Genetic Variant Detection in Leukemia Samples to Drive Blood Cancer Research Worldwide
Roche introduces the GS GType TET2/CBL/KRAS Primer Set and GS GType RUNX1 Primer Set for leukemia research. - 4/16/2012
Roche Launches Software Upgrade for GS Junior System, Announces Long Read Improvements and Workflow Automation for 2012/2013
Roche announced today the immediate availability of a new software upgrade and further upcoming sequencing performance and workflow improvements to the company’s 454 GS Junior System. - 3/14/2012
Spanish Research Team Uses Roche’s GS FLX+ System to Sequence Antibiotic Resistance Bacteria in Recent Hospital Outbreak
A team of researchers from Spain announced today the sequencing of the whole genome of three antibiotic resistant strains of Klebsiella pneunomiae isolated from a recent outbreak in a Spanish hospital. - 2/8/2012
Roche Supports the Smithsonian’s National Zoo with Next-Generation Sequencing Instrument for Animal Conservation Research
The Smithsonian Conservation Biology Institute in Washington, DC announced today a collaboration agreement to use Roche’s GS Junior benchtop sequencing system for research in SCBI’s Center for Conservation and Evolutionary Genetics. - 1/30/2012
Hamilton Introduces Automated DNA Sample Enrichment Solution using Roche 454 REM e System
Hamilton Robotics announced today a new automated solution for DNA sample enrichment on the MICROLAB STARlet Liquid Handling Workstation. - 1/17/2012
Roche´s GS Junior Sequencing System Used in Research on Personalized Tumor Treatment
IMGM Laboratories report using the GS Junior Benchtop System to sequence clinically relevant exons and identify genomic variations in solid tumors treated with an antibody-based medicine. - 10/12/2011
Roche Licenses Nanopore Sequencing Technologies from Arizona State University and Columbia University for Rapid, Affordable DNA Sequencing
The licensed technologies for DNA base sensing and reading build on an ongoing collaboration between 454 Life Sciences and IBM to develop and commercialize a single-molecule, nanopore DNA sequencer. - 9/22/2011
Roche Researchers Sequence Complete Genome of Cynomolgus Monkey and Develop Novel Gene Expression Microarray for Drug Safety Assessment
Scientists from Roche Pharma Research and Early Development and Roche NimbleGen reported in Genome Research that they have generated the first draft genome sequence of the cynomolgus monkey. - 8/18/2011
Medicinal Genomics Sequences the Cannabis Genome Using Roche’s GS FLX+ System
Medicinal Genomics announced today that it has sequenced the entire genomes of Cannabis sativa and Cannabis indica, representing two strains of the therapeutic plant. - 8/11/2011
Researchers Decode Genome of Atlantic Cod Using 454 Sequencing Systems
A team of Norwegian researchers have generated the first high-quality assembly of the Atlantic cod genome. - 7/14/2011
Roche Announces Thomas Schinecker as New President of 454 Life Sciences
Effective August 1, 2011, Dr. Thomas Schinecker is appointed Lifecycle Leader for Sequencing and President of 454 Life Sciences, Inc., in Branford, Connecticut, USA, reporting to Robert Yates, Head of Applied Science. - 6/28/2011
Roche Launches GS FLX+ System Offering High-Quality, Sanger-like Reads with the Power of Next-Generation Throughput
Early access projects have revealed the critical importance of the extended read lengths for a variety of applications including de novo sequencing, comprehensive transcriptome profiling, and metagenomic characterization of environmental samples. - 6/15/2011
Deadly E. Coli Strain Sequenced With Roche GS Junior System by HPA Scientists - Provides Community Most Complete Assembly to Date
The sequence data will assist in on-going efforts to identify the source of the outbreak, and understand how the strain may have evolved. - 5/24/2011
454 Sequencing Systems Aid in Discovery of Novel Canine Hepatitis C Virus
During an investigation to characterize respiratory viruses infecting domestic dogs, research team discovers a novel canine hepatitis C virus. - 4/6/2011
Roche Joins in Spanish Research Cooperation for Personalized Treatment of Hepatitis B and C - 4/5/2011
Roche and NuGEN Technologies Develop Whole Transcriptome Profiling Solution for 454 Sequencing Systems
Roche and NuGEN Technologies to co-promote NuGEN’s Ovation® RNA-Seq System with the GS FLX and GS Junior Systems to enable whole transcriptome profiling with low abundance RNA samples. - 3/30/2011
Roche Introduces Next-Generation HLA Typing Solution for 454 Sequencing Systems
Launch of the new GS GType HLA Primers for high- and medium-resolution genotyping with the GS FLX and GS Junior Systems. - 3/7/2011
Roche and RainDance Technologies Join Forces in Targeted Sequencing to Advance ADME Research
Collaboration to enable scientists to capture known and unknown functional mutations associated with core set of pharmacokinetic and pharmacology genes. - 1/17/2011
454 Life Sciences, University of Florida, and DOE JGI Sequence Sweet Orange Genome, Publish Annotated Assembly to Public Database
Collaborative research team sequence and assemble the first citrus genomes. - 12/7/2010
International Research Studies Underscore Utility, Robustness of 454 Sequencing Systems for Characterizing Blood Cancers
Studies presented this week at the American Society of Hematology Annual Meeting highlight the value of 454 Sequencing Systems for in-depth characterization of blood cancers, including leukemia and other hematological malignancies. - 11/1/2010
Roche Partners with DNA Electronics to Develop Semiconductor-Based Sequencing System
454 Life Sciences, a Roche Company, announced that it has entered an exclusive partnership with DNA Electronics for the development of a low-cost, high-throughput DNA sequencing system. - 10/19/2010
Roche and Fluidigm Corporation enter worldwide co-promotion agreement for 454 Sequencing Systems and Access Array™ Platform
The companies' complementary amplicon sample prep and sequencing systems offer a streamlined workflow for targeted sequencing applications. - 8/19/2010
IMGM Laboratories GmbH and the Center for Human Genetics and Laboratory Medicine to Develop Workflows for Use of 454 Sequencing Systems in Human Genetics
Two German-based sister companies to develop targeted resequencing workflows in the field of human genetics and disease. - 7/29/2010
Researchers Solve Mystery of Uner Tan Syndrome with Targeted Next-Gen Sequencing using Roche NimbleGen SeqCap and 454 Sequencing Systems
Researchers have identified the causative mutation for Uner Tan Syndrome, a rare and debilitating disease. - 7/27/2010
Results from Two Multi-Site Collaborative Studies Highlight the Value of 454 Sequencing Systems for Genotyping Applications
Two multi-site research studies use the GS FLX System to perform HIV drug-resistant mutation detection and HLA genotyping. - 7/12/2010
U.S. and Norwegian Scientists Use 454 Sequencing Systems to Identify a Novel Virus Threatening Farmed and Wild Salmon
Using 454 Sequencing Systems, an international team has found evidence that a disease threatening farmed salmon may be caused by a previously unknown virus. - 7/1/2010
Roche and IBM Collaborate to Develop Nanopore-Based DNA Sequencing Technology
Collaboration aims to accelerate human genome analysis and enable advancements in personalized healthcare. - 5/27/2010
Roche’s Newly Launched Next-Generation DNA Sequencer Opens Innovation in Genomic Research to Broad Scientific Community
GS Junior Benchtop System expected to accelerate research in life sciences and human health - 4/28/2010
Roche NimbleGen and Biogemma Develop Enhanced Sequence Capture Technology for Wheat and Canola
Biogemma has developed an improved targeted sequencing process for plant research using NimbleGen Sequence Capture and 454 Sequencing technology. - 4/22/2010
Roche Supports Science Education with Undergraduate Course on Sea Lion Genome Analysis Using 454 Sequencing Systems
San Diego State University students learn to use the Genome Sequencer FLX System to explore sea lion genomics. - 4/1/2010
454 Sequencing Study Unravels the Hidden Genomic Complexity of the Giant Mimivirus
Sequencing study offers surprising new clues into the genomic complexity of the giant Mimivirus. - 3/23/2010
454 Life Sciences’ Early Access Customers Present Promising First Sequencing Application Data with the New GS Junior System
At the analytica conference, a group of early access users shared their first results using the GS Junior System. - 3/18/2010
Targeted Sequencing in Maize Genome Utilizing a Novel Two-Stage Sequence Capture Method
Researchers from Iowa State University, University of Minnesota, University of Florida and Roche NimbleGen have published a novel method to perform targeted sequencing using the GS FLX System in the highly complex maize genome. - 2/18/2010
Research Team Publishes World’s First Southern African Genome and Multiple Exomes using 454 Sequencing and NimbleGen Sequence Capture Arrays
The Penn State-led team has used 454 Sequencing Systems and NimbleGen Sequence Capture arrays to build the first complete genome and exome sequences from the indigenous hunter-gatherer people of southern Africa, the oldest known human lineage. - 1/26/2010
454 Life Sciences Offers Simplified Sequencing Workflow with New Automation Solution for the Genome Sequencer FLX System - 1/7/2010
Saving the Devil: 454 Sequencing Study Uncovers Likely Culprit in Tasmanian Devil Transmissible Cancer
Tasmanian Devil project represents one of many ongoing wildlife management research studies to use high-throughput 454 Sequencing Systems to prevent devastation of earth’s diverse species and ecosystems. - 12/9/2009
454 Sequencing Systems and NimbleGen Sequence Capture Show Promise for Genetic Characterization of Leukemia
Researchers from the MLL Munich Leukemia Labratory explore the use of 454 Sequencing technology to detect a variety of mutations in leukemia samples. - 11/19/2009
454 Life Sciences Unveils New Bench Top Sequencer, Significant Improvements to the Genome Sequencer FLX System Including 1,000 bp Reads for 2010
The new GS Junior System will be available for sale in 2010. - 11/10/2009
Researchers Use 454 Sequencing System to Complete Draft Genome Sequence for Cassava
$1.3 Million grant from Bill & Melinda Gates Foundation will fund next phase of research that is critical to global food security. - 10/29/2009
Norwegian Team Completes Cod Genome Using 454 Sequencing System
Researchers have performed de novo sequencing and assembly of the Atlantic cod genome in order to identify genes and genetic variations underlying important traits for cod aquaculture. - 10/27/2009
Roche Molecular Systems Research Team Uses 454 Sequencing System for High-Resolution HLA Genotyping
Accurate human leukocyte antigen (HLA) genotyping is critical to research on a variety of human diseases, as well as tissue transplantation. - 10/13/2009
Landmark Genotyping Study Demonstrates the Power of 454 Sequencing Systems for Immunogenetics
Researchers have used the Genome Sequencer FLX System to perform rapid major histocompatibility complex (MHC) class I genotyping in macaques. - 9/29/2009
SAIC-Frederick and Roche Enter into a Research Collaboration on Technology Advancements for Cancer Gene Sequencing.
SAIC-Frederick will use Roche NimbleGen Sequence Capture arrays and 454 Sequencing systems to perform cancer gene sequencing. - 8/5/2009
454 Life Sciences and Roche NimbleGen Announce Collaboration with Eli Lilly and SeqWright to Sequence Genomic Regions Associated with Psychiatric Disease. - 7/29/2009
Roche and Google.org Start Initiative for Early Discovery of New Diseases - 7/16/2009
Researchers to Decode Antarctic Ice Metagenome with the 454 Sequencing System, to Explore the Effects of Climate Change
Researchers in Germany will use their runner-up 10GB sequencing award to explore the arctic metagenome. - 7/8/2009
The Research Institute of the Hospital Universitari Vall d'Hebron is the first Spanish Health Centre to Acquire High-Performance Sequencing Technology of 454 Life Sciences.
The Research Institute of the Hospital Universitari Vall d'Hebron (IR-HUVH) in Barcelona is the first Spanish health centre to acquire the Genome Sequencer FLX System from 454 Life Sciences, a Roche company. - 6/25/2009
Roche Applied Science Announces Winners of 454 Life Sciences’ 10GB Grant Program
The two first-place winners will use the 10GB sequencing award to study African sleeping sickness drug resistance and ant fungal garden metagenomes. - 6/11/2009
454 Life Sciences Celebrates a Revolution in Genomics - Announces the 454th Peer-Reviewed Publication Using the Genome Sequencer System
454 Life Sciences, a Roche company, celebrates the 454th peer-reviewed publication enabled by the Genome Sequencer System. - 6/5/2009
Roche and SeqWright Collaborate to Help Elucidate the Underlying Genetic Causes of Heart Disease - 6/3/2009
The 454 Genome Sequencing System Detects a Novel Virus Responsible for South African Hemorrhagic Fever Outbreak
The newly discovered arenavirus caused the deaths of four of five infected individuals in South Africa in October, 2008. - 5/12/2009
454 Sequencing Systems Enable High Quality De Novo Assembly of Oil Palm Genome - 4/23/2009
454 Life Sciences Announces Comprehensive Solution for De Novo Sequencing and Assembly of Increasingly Complex Genomes
The GS FLX Titanium Series multi-span paired end kits and improved assembler software solidify 454 Sequencing System’s position as the technology of choice for de novo sequencing applications. - 4/7/2009
Researchers Uncover Low-Frequency Hepatitis B Drug-Resistant Mutations Using 454 Sequencing Systems
Study results show improved sensitivity for detecting low-prevalence resistance variants when compared to traditional methods. - 4/2/2009
454 Sequencing Boosts Genomics Research in Spain: Genome Sequencer FLX System Installed at University of Barcelona - 3/5/2009
Next-Generation Sequencing Uncovers Genetic Variation Linking Type 1 Diabetes with Enterovirus Infection
Science study discovers rare mutations in a disease-associated antiviral response gene that reduce the risk developing type 1 diabetes. - 3/4/2009
Researchers Use 454 Sequencing System for Rapid Sequencing of Avian Influenzas - 2/18/2009
454 Sequencing Study Reveals New Insights in Drug Resistance and Tropism Associated with the New HIV Integrase and Entry Inhibitor Therapy Classes
Research study results may have potential implications for therapy selection in HIV patients in the future. - 2/17/2009
454 Sequencing Identifies Early Stage HIV Drug Resistance-- Low-level Mutations may have Significant Impact on Clinical Outcomes
Retrospective research study shows that even the lowest levels of resistance mutations could lead to early treatment failure. - 2/12/2009
454 Life Sciences and Max Planck Institute Complete Draft 1X Sequence of Neanderthal Genome
Completion of >3 billion bases of Neanderthal DNA brings closure to the sequencing stage of an ambitious project initiated two years ago. Announcement of bonobo genome draft sequence opens new doors to understanding the evolution of humans and apes. - 2/3/2009
Roche NimbleGen and 454 Life Sciences Capture the Targeted Resequencing Market on a Global Scale
NimbleGen Sequence Capture microarrays are quickly becoming the sample preparation method of choice for high-throughput sequencing laboratories around the world. - 1/29/2009
454 Sequencing Helps Identify Herpes-like Viruses That May Contribute to Pandemic Decline of Tropical Reefs - 1/27/2009
Roche Applied Science Makes Exome Sequencing a Reality, a Giant Step Towards Personalized Medicine
Capture all human protein coding and miRNA exons on a single NimbleGen microarray and sequence with the Genome Sequencer FLX System from 454 Life Sciences. - 12/18/2008
Researchers Successfully Use the 454 Sequencing System for Sensitive Detection of HIV Tropism
454 Sequencing accurately detects HIV tropism in patient samples and identifies low-frequency variants associated with poor response to CCR5 antagonist therapies. - 12/3/2008
Nature Study Uses 454 Sequencing to Reveal Surprising New Clues into the Role of Microbial Communities in the Human Gut
Study demonstrates the importance of long sequencing reads for accurate assignment against metagenomic databases. - 12/1/2008
454 Life Sciences Joins in Worldwide Roche Walk to Support Children in Malawi - 11/20/2008
Open-source Analysis Tool Enables Rapid Annotation of Metagenomes
The new metagenomic RAST server is designed specifically for use with data generated by 454 Sequencing™ systems. - 11/13/2008
Discovery of Mysterious Microbe Offers New Insights into Ocean Ecosystem.
Metagenomic study marks the first published paper using the new GS FLX Titanium reagents for the 454 Sequencing system. - 11/6/2008
A virus-infecting virus: Researchers use the 454 Sequencing System to identify a novel small virus parasitic to another virus. - 11/4/2008
Roche NimbleGen and Baylor College develop an improved version of Sequence Capture 385K Arrays for target region sequencing with the GS FLX System
New Sequence Capture algorithms result in more uniform coverage, less overall sequencing costs, and enables whole exome sequencing. - 10/1/2008
454 Life Sciences Launches the GS FLX Titanium Series Reagents, Effectively Replacing Traditional Sanger Sequencing
454 Sequencing launches the new GS FLX Titaniums series reagents for use on the current Genome Sequencer FLX Instrument. - 9/30/2008
454 Life Sciences and GenomeQuest Team Up to Provide Next-Generation Sequence Search and Analysis Services
GenomeQuest will offer new On-Demand Informatics Service to users of the 454 Genome Sequencer FLX System. - 9/24/2008
Roche Diagnostics and Integrated DNA Technologies to Enter Worldwide Exclusive Agreement for Primer Design and Supply - 9/23/2008
250th Peer-reviewed Publication Documents the Success of 454 Sequencing
The 454 Genome Sequencer System accelerates the pace of discovery in diverse fields of biology. - 8/18/2008
454 Sequencing System Opens New Avenue in Prostate Cancer Research
Researchers use the GS FLX System to identify genetic variations linked to cancers. - 8/8/2008
Roche´s 454 Sequencing System Used to Determine the Complete Neanderthal Mitochondrial Genome, Establishing When Humans and Neanderthals Diverged
Researchers use 454's Genome Sequencer FLX systems to sequence the complete Neanderthal mitochondrial genome. - 8/5/2008
AGOWA Genomics Adds the Roche Genome Sequencer FLX System to Its Sequencing Portfolio
AGOWA Genomics adds a Genome Sequencer FLX system to expand service offering. - 7/17/2008
Roche and Oxford University: Cooperation to Evaluate 454 Sequencing and NimbleGen High-Density Arrays for Genetic Disease Analysis
The Oxford Biomedical Research Centre will use 454 Sequencing and Roche NimbleGen's high-density arrays to create improved solutions for the analysis of genetic diseases. - 7/10/2008
454 Genome Sequencer FLX System plus NimbleGen Sequence Capture Arrays Help Unravel the Cryptic Genetic Changes in Hematological Malignancies
The Cancer Genomics Group at Barts and The London Medical School to study leukemia using 454 Sequencing and Roche NimbleGen Sequence Capture arrays. - 6/27/2008
454 Sequencing at the Forefront of Bone Marrow and Stem Cell Therapy Research
Roche Genome Sequencer FLX System creates new opportunities for HLA research at the Blood Centre Linz, Austria - 6/12/2008
One Run - Done: 454 Sequencing Quickly Reveals Detailed Insights Into the Physiology of Corynebacterium kroppenstedtii
Researchers at Bielefeld University in Germany have used a single sequencing run to completely assemble and characterize the genome of Corynebacterium kroppenstedtii. - 6/11/2008
454 Sequencing Joins the International 1000 Genomes Project
Continuing Roche’s commitment to support human genomic research, 454 Sequencing will deliver results of the highest quality and completeness to international research effort. - 6/5/2008
454 Sequencing for Melon Research in Spain
Study at the Center of Research in Agronomics in Barcelona, Spain focuses on the de novo sequencing of the musk melon - 5/30/2008
454 Life Sciences, Cogenics, and Limagrain to Jointly Develop Solutions for Crop SNP Discovery with Next Generation Sequencing
Partners Will Co-Develop Genomic Complexity Reduction Methods for Crop Genomes Initial Study to Focus on Wheat Genome - 5/21/2008
454 Sequencing Used at Institute of Genomics & Integrative Biology (IGIB) in India
IGIB plans to use their new Genome Sequencer FLX System system for all applications possible within this revolutionary technology, with a special focus on metagenomics and de novo genome sequencing - 5/8/2008
454 Sequencing for the Characterization of the Protective Intestinal Flora - 4/30/2008
Reconstructing Oetzi, the Neolithic Man family tree with 454 Sequencing
Reconstructing Oetzi’s family tree with 454 Sequencing gives unprecedented insight into Neolithic Man. - 4/17/2008
Researchers Use 454 Sequencing to Publish the Complete Genome of an Individual Human, Achieving a Key Milestone on the Path to Personalized Genome Sequencing
Study in Nature establishes quality standard for the routine sequencing of humans - 4/16/2008
Top European Service provider GATC ramps up its fleet of next-gen sequencers with second GS FLX
GATC Biotech, one of Europe’s leading sequencing service providers, has acquired a second Genome Sequencer FLX System. - 4/15/2008
MWG Biotech purchases second Genome Sequencer FLX system to expand capacities in line with growing sequencing demand
MWG Biotech, a European market leader in genome sequencing services, is further expanding its 454 Sequencing capacity in order to meet the demands of a steadily increasing number of sequencing customers across Europe. - 2/25/2008
Researchers Use Transcriptome Analysis by 454 Sequencing to Identify Tumor Specific Mutations Linked to Malignent Pleural Mesothelioma
Researchers have used the 454 long-read sequencing technology to characterize for the first time mutations in expressed genes unique to malignant pleural mesotheliomas (MPMs) - 2/8/2008
Transplantation Safety: New Virus Detected Using Genome Sequencer Technology
Researchers at Columbia University and Victorian Infectious Disease Reference Laboratory have discovered a new virus that was responsible for the deaths of three transplant recipients. - 2/7/2008
The Genome Sequencing Center at Washington University School of Medicine increases fleet of Roche Genome Sequencer FLX Systems to Eight Instruments
The Genome Sequencing Center at Washington University School of Medicine increased its sequencing capacity with an agreement to acquire five additional Genome Sequencer FLX Systems from Roche Diagnostics. - 2/4/2008
Roche Further Improves Cost Effectiveness and Application Versatility in Sequencing: New Long-Tag Paired End Reads and Multiplex Identifiers for the Genome Sequencer FLX System
454 Life Sciences, a part of Roche Applied Science, today announced the launch of new products and software for the ultra-high throughput Genome Sequencer FLX System (GS FLX) - 12/19/2007
Researchers use the Genome Sequencer System to sequence and assemble the Pinot Noir Genome.
Researchers from the Istituto Agrario San Michele all'Adige and Myriad Genetics have used the Genome Sequencer 20 System, to sequence and assemble the genome of the grape species Pinot Noir. - 11/12/2007
The Max Planck Institute in Leipzig acquires second Genome Sequencing FLX™ System.
454 Life Sciences, a part of Roche Applied Science, today announced that the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany has purchased its second Genome Sequencer FLX (GS FLX) System. - 11/6/2007
A Life Sciences Renaissance: 100th peer-reviewed publication enabled by 454 Sequencing™
454 Life Sciences, a Roche company, today announced the publication of over 100 peer-reviewed studies using the Company’s Genome Sequencer System. - 10/23/2007
The Human Genome Sequencing Center at Baylor College of Medicine increases fleet of Roche Genome Sequencer FLX Systems to 10 Instruments
The Human Genome Sequencing Center at Baylor College of Medicine boosted its sequencing capabilities with an agreement to acquire seven additional Genome Sequencer FLX Systems from 454 Life Sciences, a Roche company. - 9/27/2007
New Pharmacogenomic Approach: 454 Life Science and Perlegen to Collaborate in Drug Response Sequencing Study
454 Life Sciences, a Roche company, and Perlegen Sciences, Inc., today announced a collaboration to conduct large scale genetic re-sequencing for drug response. - 9/27/2007
454 Sequencing™: Science Paper Suggests that Structural Variation Plays an Important Role in Genetic Variation
454 Life Sciences, a Roche company, in collaboration with Yale University researchers today announced that they have developed a method to identify significant human genetic variability with an unprecedented level of detail. - 9/27/2007
454 Sequencing™: Science Paper describes a novel, highly efficient method of sequencing ancient DNA, and sequences the mitochondria of 10 individual Mammoths to prove it.
454 Life Sciences, a Roche company, today reported that researchers from Pennsylvania State University have used the company’s Genome Sequencer™ FLX system to sequencing the entire mitochondrial genomes from 10 individual woolly mammoths. - 9/27/2007
Versatility of 454 Sequencing™ Demonstrated in Three Publications in Science this Week
454 Life Sciences, a Roche company, is the subject of three ground-breaking studies published this week in Science, all of which employed the company’s Genome Sequencer™ system. - 9/27/2007
454 Sequencing™ in Science Today: Researchers Uncover a Genetic Basis for Different Social Behaviors in Wasp.
454 Life Sciences, a Roche company, in collaboration with researchers from the University of Illinois at Urbana-Champaign today announced that they have uncovered genetic underpinnings to social behavior in wasps. - 9/6/2007
Researchers Identify Virus Possibly Responsible for Declining Honeybee Population Using 454 Sequencing Technology from Roche
454 Life Sciences, a Roche company, today announced that researchers at Columbia University, in collaboration with 454, have identified a virus implicated in the deaths of 2.4 million honeybee colonies using the company’s Genome Sequencer™ system. - 8/30/2007
Roche Applied Science and 454 Life Sciences improve the Genome Sequencer FLX workflow and help reduce instrument run costs
454 Life Sciences, the sequencing center of excellence of Roche Applied Science today announced the launch of new products and software for the ultra high-throughput Genome Sequencer FLX System (GS FLX). - 6/15/2007
454 Sequencing(TM) Identifies HIV Drug Resistance at Early Stage
- Retrospective study shows that even the lowest levels of resistance mutations can lead to early treatment failure - - 5/31/2007
454 Life Sciences and Baylor College of Medicine Complete Sequencing of DNA Project
-The Genome of James Watson is the First to be Sequenced for Less than $1 Million- - 5/29/2007
454 LIFE SCIENCES ANNOUNCES THE COMPLETION OF ITS ACQUISITION BY ROCHE
The acquisition of 454 Life Sciences by Roche is finalized and made official. - 3/29/2007
CuraGen Announces Definitive Agreement to Sell 454 Life Sciences to Roche
CuraGen Corporation (Nasdaq: CRGN) and Roche today announced that 454 Life Sciences and Roche have signed a definitive merger agreement under which Roche will acquire 454 Life Sciences Corporation, a majority-owned subsidiary of CuraGen Corporation. - 3/1/2007
454 Sequencing Reveals Novel Aspects of a Human Pathogen
454 Life Sciences Corp. today announced that researchers at Yale University using the company's Genome Sequencer system have determined the pathogenic content of A. baumannii. - 1/8/2007
454 Life Sciences Ships First Genome Sequencer FLX System(TM) to Roche Diagnostics
454 Life Sciences Corporation today announced that the new high throughput Genome Sequencer FLX System(TM) (GS FLX) has been shipped to its marketing partner Roche Diagnostics in preparation for a first quarter 2007 launch. - 12/21/2006
454 Sequencing Reveals New Class of Small RNAs
454 Life Sciences Corporation today announced that researchers have uncovered a new class of small, non-coding RNAs in worms. Application by Massachusetts Institute of Technology Yields New Insights on Gene Regulation - 12/19/2006
The World Economic Forum Announces Technology Pioneers 2007: 454 Life Sciences Selected
The World Economic Forum recently announced the 47 Technology Pioneers for 2007. 454 Life Sciences Corporation has been selected as one of these Technology Pioneers. - 11/20/2006
454 Life Sciences Named to 2006 Scientific American 50
454 Life Sciences Corporation has been named by Scientific American magazine as one of this year's "Scientific American 50". - 11/15/2006
454 Life Sciences and Max Planck Publish Sequence of One Million Base Pairs
454 Life Sciences Corporation today announced that comparison of the human and chimpanzee genomes to Neandertal DNA sequences determined by 454 Sequencing™ reveals that modern human and Neandertal DNA sequences diverged about 500,000 years ago. - 10/25/2006
454 Sequencing™ Reveals New Pathway in RNA Interference
454 Life Sciences today announced that research on small RNAs, conducted by Cold Spring Harbor Laboratory, has revealed the dual role of the ARGONAUTE 4 protein (AGO4) in RNA-directed DNA methylation. - 9/6/2006
International Census of Marine Microbes Reveals a Greater Level of Marine Diversity Using Ultrafast Sequencing System from Roche Diagnostics
Roche Applied Science and 454 Life Sciences Corporation today announced that the International Census of Marine Microbes has purchased a Genome Sequencer 20(TM) system as part of a multi-institutional study of microbial life in the world's oceans. - 8/31/2006
454 Life Sciences' Genome Sequencer 20(TM) Wins R&D 100 Award
454 Life Sciences Corporation, announced today its Genome Sequencer 20(TM) system has received an R&D 100 Award as one of the most technologically significant products introduced into the marketplace during the past year. - 7/20/2006
454 Life Sciences and Max Planck Institute to Sequence Neandertal Genome
454 Life Sciences Corporation in collaboration with scientists at the Max Planck Institute for Evolutionary Anthropology, announced today in Leipzig, Germany the launch of a project to sequence the complete Neandertal genome. - 6/25/2006
Dana Farber and 454 Life Sciences Announce Breakthrough in DNA Sequencing for Cancer Research
454 Life Sciences Corporation, in collaboration with scientists at Dana Farber Cancer Center and Broad Institute, today reported a new method for the detection of cancer gene mutations present at extremely low levels. - 4/26/2006
454 Life Sciences and Roche Diagnostics Announce Updated Version of the Genome Sequencer 20(TM) System
New Genome Sequencer 20 System shows a single read accuracy of greater than or equal to 99% and additional enhanced features - 1/27/2006
NCBI Adopts Standard for Accepting 454 Life Sciences' Sequencing Data
454 Life Sciences Corporation announced today that the National Center for Biotechnology Information has added a new standard submission format for its Trace Archive of sequencing data. - 1/24/2006
454 Life Sciences Announces Katherine Webster Joins Team as Vice President of MSC Sales
454 Life Sciences Corporation announced today that Katherine Webster has joined the company as Vice President for Measurement Services Center Sales. - 1/12/2006
Keygene Selects 454 Life Sciences' Novel Sequencing Technology to Enable Large-Scale SNP Discovery and Detection in Higher Eukaryotic Organisms
454 Life Sciences Corporation announced today that its Genome Sequencer 20 system has been selected and purchased by Keygene N.V. to enable its proprietary Complexity Reduction of Polymorphic Sequences (CRoPS(TM)) technology. - 1/11/2006
454 Life Sciences Installs Twenty GS20 Systems in the First Year of Sales
454 Life Sciences Corporation announced today that in 2005 a total of twenty Genome Sequencer 20 systems were purchased by and installed with customers world-wide. - 12/19/2005
454 Life Sciences Initiates Collaborative Research Agreement with the Broad Institute
454 Life Sciences Corporation announced today the initiation of a collaborative research agreement with the Broad Institute. Researchers at the Broad Institute will use 454 Life Sciences' system to conduct disease-related genomic studies. - 12/14/2005
National Center for Genome Resources Selects 454 Life Sciences’ Novel Sequencing Technology to Sequence Genome of Major Fungal Pathogen of Vegetable Crops
454 Life Sciences Corporation has been selected by the National Center for Genome Resources to sequence the major pathogen of vegetable crops, Phytophthora capsici. The 65Mb genome will be sequenced at 454's Measurement Services Center. - 12/7/2005
454 Life Sciences and the Genome Sequencing Center at Washington University School of Medicine in St. Louis Announce Collaborative Research Plan
454 Life Sciences Corporation and the Genome Sequencing Center at Washington University School of Medicine announced a collaborative research plan to sequence disease-causing pathogens and to sequence RNA to analyze gene activity in tissue samples. - 11/9/2005
454 Life Sciences Receives Best of What’s New Award from Popular Science Magazine in Global Competition
Company Honored in Personal Health Category For its Genome Sequencer 20 System - 11/1/2005
454 Life Sciences to Present at the Rodman & Renshaw
454 Life Sciences Corporation today announced that President and Chief Executive Officer, Christopher K. McLeod, will present at the Rodman & Renshaw Techvest 7th Annual Healthcare Conference. - 10/25/2005
454 Life Sciences Receives Gold Award from the Wall Street Journal in Global Technology Innovation Competition
Company Honored for its Revolutionary Low-cost Genome Sequencing Method - 10/16/2005
President and CEO of 454 Life Sciences to Participate in
454 Life Sciences Corporation, a majority-owned subsidiary of CuraGen Corporation (Nasdaq: CRGN), today announced that President and Chief Executive Officer, Christopher K. McLeod, will participate in a panel discussion at BIO InvestorForum 2005. - 10/7/2005
454 Life Sciences and Roche Announce Commercial Launch of
454 Life Sciences to receive $7.5 million from Roche for achieving commercialization milestone - 8/1/2005
454 Life Sciences Publishes Breakthrough Genome Sequencing Technique
Microfabrication Allows Sequencing in Record Time Article Published in Nature July 31 Online Edition - 7/26/2005
454 Life Sciences Receives $11.5 Million in Milestones from Roche
454 Life Sciences, a majority-owned subsidiary of CuraGen Corporation (Nasdaq: CRGN), today announced the achievement of all initial milestones under their exclusive world-wide agreement with Roche. - 4/25/2005
454 Life Sciences Installs First Genome Sequencing System at the Broad Institute
- Technology allows leading researchers to read genomes up to 100 times faster - - 12/20/2004
Study on First New Potential Drug for Tuberculosis in 40 Years Aided by
-- Routine whole genome sequencing ushers in a new age of medicine -- - 10/14/2004
454 Life Sciences Receives $5 million NIH Grant for
Award recognizes the potential of 454 Life Sciences' technology to routinely sequence individual human genomes - 5/19/2004
454 Life Sciences Receives $2.4 million NIH Grant for Next Generation Whole Genome Picoliter-Scale Sequencing Technology
454 Life Sciences, a majority-owned subsidiary of CuraGen Corporation (Nasdaq: CRGN), today announced that the Company has received a two-year, $2.4 million grant from the National Human Genome Research Institute (NHGRI). - 11/18/2003
454 Life Sciences Announces Publication Describing Proprietary Technology for Massively Parallel DNA Amplificatio
Enabling technology for miniaturized DNA amplification is described in the journal Electrophoresis. - 9/18/2003
454 Life Sciences Secures $20 Million in Equity Financing to Initiate Commercialization of Whole Genome Sequencing Technology
54 Life Sciences, an innovative developer of genome-scale analysis technologies and a majority-owned subsidiary of CuraGen Corporation (Nasdaq: CRGN), today announced that it raised $20 million from existing shareholders. - 8/21/2003
454 Life Sciences Completes First Whole Genome Sequence Using First Novel Technology Since 1977 Invention of DNA Sequencing
Complete Adenovirus sequence submitted to GenBank(R) generated by first sequencing method designed to sequence whole genomes not genes. - 8/19/2003
454 Life Sciences Obtains Exclusive License from Pyrosequencing AB to Next Generation Sequencing Technology for Whole Genome Applications
54 Life Sciences, today announced that the Company has obtained an exclusive license for sole use of sequencing by synthesis and pyrophosphate based sequencing for whole genome applications from Pyrosequencing AB (Stockholm: PYRO A). - 8/11/2003
454 Life Sciences Announces New Appointments to the Company's Scientific Advisory Board
Three leading scientists to lend their sequencing and infectious disease expertise to 454 Life Sciences as the Company's whole genome sequencing efforts accelerate - 3/11/2003
Dr. Eugene Myers Appointed to 454 Life Sciences' Scientific Advisory Board
Dr. Eugene Myers Appointed to 454 Life Sciences' Scientific Advisory Board. Former Vice President of Informatics Research at Celera Genomics To Provide Bioinformatics Guidance to 454. - 2/12/2002
454 Corporation Names Richard F. Begley as President and Chief Executive Office
Former Agilent Executive to Head CuraGen's Technology Subsidiary.