454 Life Sciences

Diverse somatic mutation patterns and pathway alterations in human cancers.  Kan Z et al. (7/30/2010) Nature ePub:
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Genome remodelling in a basal-like breast cancer metastasis and xenograft.  Ding L et al. (4/15/2010) Nature 464(7291): 999-1005.
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A transposon-based genetic screen in mice identifies genes altered in colorectal cancer.  Starr TK, Allaei R, Silverstein KA, Staggs RA, Sarver AL, Bergemann TL, Gupta M, O'Sullivan MG, Matise I, Dupuy AJ, Collier LS, Powers S, Oberg AL, Asmann YW, Thibodeau SN, Tessarollo L, Copeland NG, Jenkins NA, Cormier RT, Largaespada DA. (3/27/2009) Science 323(5922): 1747-50.
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Nested Patch PCR enables highly multiplexed mutation discovery in candidate genes.  Varley KE, Mitra RD. (11/1/2008) Genome Research 18: 1844-50
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Somatic mutations affect key pathways in lung adenocarcinoma.  Ding L et al. (10/23/2008) Nature 455: 1069-75
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Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing.  Campbell PJ, Pleasance ED, Stephens PJ, Dicks E, Rance R, Goodhead I, Follows GA, Green AR, Futreal PA, Stratton MR. (9/2/2008) PNAS 105: 13081-6
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Direct resequencing of the complete ERBB2 coding sequence reveals an absence of activating mutations in ERBB2 amplified breast cancer  Zito CI, Riches D, Kolmakova J, Simons J, Egholm M, Stern DF. (7/1/2008) Genes Chromosomes Cancer 47: 633-638
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Multigene amplification and massively parallel sequencing for cancer mutation discovery  Fredrik Dahl, Johan Stenberg, Simon Fredriksson, Katrina Welch, Michael Zhang, Mats Nilsson, David Bicknell, Walter F. Bodmer, Ronald W. Davis, and Hanlee Ji (5/29/2007) PNAS 104: 9387–9392
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High-throughput oncogene mutation profiling in human cancer  Roman K Thomas, Alissa C Baker, Ralph M DeBiasi, Wendy Winckler, Thomas LaFramboise, William M Lin, Meng Wang, Whei Feng, Thomas Zander, Laura E MacConnaill, Jeffrey C Lee, Rick Nicoletti, Charlie Hatton, Mary Goyette, Luc Girard, Kuntal Majmudar, Liuda Ziaugra, Kwok-Kin Wong, Stacey Gabriel, Rameen Beroukhim, Michael Peyton, Jordi Barretina, Amit Dutt, Caroline Emery, Heidi Greulich, Kinjal Shah, Hidefumi Sasaki, Adi Gazdar, John Minna, Scott A Armstrong, Ingo K Mellinghoff, F Stephen Hodi, Glenn Dranoff, Paul S Mischel, Tim F Cloughesy, Stan F Nelson, Linda M Liau, Kirsten Mertz, Mark A Rubin, Holger Moch, Massimo Loda, William Catalona, Jonathan Fletcher, Sabina Signoretti, Frederic Kaye, Kenneth C Anderson, George D Demetri1, Reinhard Dummer, Stephan Wagner, Meenhard Herlyn, William R Sellers, Matthew Meyerson & Levi A Garraway (3/1/2007) Nature Genetics 39: 347-351
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Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing  Roman K Thomas, Elizabeth Nickerson, Jan F Simons, Pasi A Janne, Torstein Tengs, Yuki Yuza, Levi A Garraway, Thomas LaFramboise, Jeffrey C Lee, Kinjal Shah, Keith O’Neill, Hidefumi Sasaki, Neal Lindeman, Kwok-Kin Wong, Ana M Borras, Edward J Gutmann, Konstantin H Dragnev, Ralph DeBiasi, Tzu-Hsiu Chen, Karen A Glatt, Heidi Greulich, Brian Desany, Christine K Lubeski, William Brockman, Pablo Alvarez, Stephen K Hutchison, J H Leamon, Michael T Ronan, Gregory S Turenchalk, Michael Egholm, William R Sellers, Jonathan M Rothberg & Matthew Meyerson (6/26/2006) Nature Medicine 12: 852-855
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